Mechanistic insight into a novel synthetic cantharidin analogue in a leukaemia model

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Mechanistic insight into a novel synthetic cantharidin analogue in a leukaemia model.

Cantharidin isolated from Mylabris caraganae and other insects is used traditionally as an anti-cancer drug especially on hepatoma and leukaemia. Previously, we demonstrated that the novel synthetic cantharidin analogue CAN 032 possessed apoptotic activity on two human hepatoma cell lines Hep3B hepatocellular carcinoma and SK-Hep-1 liver adenocarcinoma. However, its underlying mechanistic actio...

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ژورنال

عنوان ژورنال: International Journal of Molecular Medicine

سال: 2006

ISSN: 1107-3756,1791-244X

DOI: 10.3892/ijmm.18.2.375